The glucosaminidase domain of Atl – the major Staphylococcus aureus autolysin – has DNA-binding activity

In this communication, we describe evidence demonstrating the capacity of Atl, the major Staphylococcus aureus autolytic enzyme to bind DNA. Electrophoretic mobility shift assays (EMSA) show that both the Atl protein and the endo-β-N-acetylglucosaminidase (GL) domain were able to bind DNA of nonspec...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Grilo, Inês R, Ludovice, Ana Madalena, Tomasz, Alexander, de Lencastre, Hermínia, Sobral, Rita G
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley & Sons Ltd. 2014
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996572/
https://ncbi.nlm.nih.gov/pubmed/24585695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.165
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