The glucosaminidase domain of Atl – the major Staphylococcus aureus autolysin – has DNA-binding activity

In this communication, we describe evidence demonstrating the capacity of Atl, the major Staphylococcus aureus autolytic enzyme to bind DNA. Electrophoretic mobility shift assays (EMSA) show that both the Atl protein and the endo-β-N-acetylglucosaminidase (GL) domain were able to bind DNA of nonspec...

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Bibliografische gegevens
Hoofdauteurs: Grilo, Inês R, Ludovice, Ana Madalena, Tomasz, Alexander, de Lencastre, Hermínia, Sobral, Rita G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley & Sons Ltd. 2014
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996572/
https://ncbi.nlm.nih.gov/pubmed/24585695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.165
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