The glucosaminidase domain of Atl – the major Staphylococcus aureus autolysin – has DNA-binding activity

In this communication, we describe evidence demonstrating the capacity of Atl, the major Staphylococcus aureus autolytic enzyme to bind DNA. Electrophoretic mobility shift assays (EMSA) show that both the Atl protein and the endo-β-N-acetylglucosaminidase (GL) domain were able to bind DNA of nonspec...

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Hlavní autoři: Grilo, Inês R, Ludovice, Ana Madalena, Tomasz, Alexander, de Lencastre, Hermínia, Sobral, Rita G
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons Ltd. 2014
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996572/
https://ncbi.nlm.nih.gov/pubmed/24585695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.165
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