The glucosaminidase domain of Atl – the major Staphylococcus aureus autolysin – has DNA-binding activity

In this communication, we describe evidence demonstrating the capacity of Atl, the major Staphylococcus aureus autolytic enzyme to bind DNA. Electrophoretic mobility shift assays (EMSA) show that both the Atl protein and the endo-β-N-acetylglucosaminidase (GL) domain were able to bind DNA of nonspec...

Full description

Saved in:
Bibliographic Details
Main Authors: Grilo, Inês R, Ludovice, Ana Madalena, Tomasz, Alexander, de Lencastre, Hermínia, Sobral, Rita G
Format: Artigo
Language:Inglês
Published: John Wiley & Sons Ltd. 2014
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996572/
https://ncbi.nlm.nih.gov/pubmed/24585695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mbo3.165
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items