cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase.

The L-arginine:nitric oxide (NO) pathway is believed to exert many of its physiological effects via stimulation of the soluble guanylyl cyclase (SGC); however, the lack of a selective inhibitor of this enzyme has prevented conclusive demonstration of this mechanism of action. We have found that the...

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Hauptverfasser: Moro, M A, Russel, R J, Cellek, S, Lizasoain, I, Su, Y, Darley-Usmar, V M, Radomski, M W, Moncada, S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC39965/
https://ncbi.nlm.nih.gov/pubmed/8643658
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