cGMP mediates the vascular and platelet actions of nitric oxide: confirmation using an inhibitor of the soluble guanylyl cyclase.

The L-arginine:nitric oxide (NO) pathway is believed to exert many of its physiological effects via stimulation of the soluble guanylyl cyclase (SGC); however, the lack of a selective inhibitor of this enzyme has prevented conclusive demonstration of this mechanism of action. We have found that the...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Moro, M A, Russel, R J, Cellek, S, Lizasoain, I, Su, Y, Darley-Usmar, V M, Radomski, M W, Moncada, S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39965/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643658/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.4.1480
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