Role of Nitric Oxide, Nitric Oxide Synthase, Soluble Guanylyl Cyclase, and cGMP-Dependent Protein Kinase I in Mouse Stem Cell Cardiac Development

Introduction and Aim. Nitric oxide (NO) can trigger cardiac differentiation of embryonic stem cells (ESCs), indicating a cardiogenic function of the NO synthetizing enzyme(s) (NOS). However, the involvement of the NO/NOS downstream effectors soluble guanylyl cyclase (sGC) and cGMP activated protein...

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Publicado en:Stem Cells Int
Autores principales: Spinelli, Valentina, Vona, Alessia, Corti, Francesca, Diolaiuti, Lorenzo, Zanardelli, Matteo, Sartiani, Laura, Failli, Paola
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5093303/
https://ncbi.nlm.nih.gov/pubmed/27840646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2868323
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