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Enhanced Antitumor Efficacy of an Oncolytic Herpes Simplex Virus Expressing an Endostatin–Angiostatin Fusion Gene in Human Glioblastoma Stem Cell Xenografts

Viruses have demonstrated strong potential for the therapeutic targeting of glioblastoma stem cells (GSCs). In this study, the use of a herpes simplex virus carrying endostatin–angiostatin (VAE) as a novel therapeutic targeting strategy for glioblastoma-derived cancer stem cells was investigated. We...

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Detalhes bibliográficos
Principais autores: Zhang, Guobin, Jin, Guishan, Nie, Xiutao, Mi, Ruifang, Zhu, Guidong, Jia, William, Liu, Fusheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995956/
https://ncbi.nlm.nih.gov/pubmed/24755877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095872
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