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Direct Thrombin Inhibitor Argatroban Reduces Stroke Damage in Two Different Models

BACKGROUND AND PURPOSE: We showed previously robust neuroprotection with the thrombin inhibitor argatroban, and now sought additional support for its neuroprotective potential. METHODS: We used behavioral and histological endpoints; rigorously blinded the study groups; extended the treatment window...

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Autors principals: Lyden, Patrick, Pereira, Benedict, Che, Bo, Zhao, Lifu, Lamb, Jessica, Le, I-farn, Rajput, Padmesh
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995814/
https://ncbi.nlm.nih.gov/pubmed/24473182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.113.004488
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