Concurrent Middle Cerebral Artery Occlusion and Intra-arterial Drug Infusion via Ipsilateral Common Carotid Artery Catheter in the Rat

Pre-clinical development of therapy for acute ischemic stroke requires robust animal models; the rodent middle cerebral artery occlusion (MCAo) model using a nylon filament inserted into the internal carotid artery is the most popular. Drug screening requires targeted delivery of test substance in a...

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Main Authors: Van Winkle, Jessica A., Chen, Bo, Lei, I-Farn, Pereira, Benedict, Rajput, Padmesh S., Lyden, Patrick D.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570629/
https://ncbi.nlm.nih.gov/pubmed/23261656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2012.12.004
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