Intra-Ophthalmic Artery Chemotherapy Triggers Vascular Toxicity through Endothelial Cell Inflammation and Leukostasis

PURPOSE. Super-selective intra-ophthalmic artery chemotherapy (SSIOAC) is an eye-targeted drug-delivery strategy to treat retinoblastoma, the most prevalent primary ocular malignancy in children. Unfortunately, recent clinical reports associate adverse vascular toxicities with SSIOAC using melphalan...

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Detalhes bibliográficos
Main Authors: Steinle, Jena J., Zhang, Qiuhua, Thompson, Karin Emmons, Toutounchian, Jordan, Yates, C. Ryan, Soderland, Carl, Wang, Fan, Stewart, Clinton F., Haik, Barrett G., Williams, J. Scott, Jackson, J. Scott, Mandrell, Timothy D., Johnson, Dianna, Wilson, Matthew W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995559/
https://ncbi.nlm.nih.gov/pubmed/22427570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9466
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