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Increased diacylglycerol kinase ζ expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion

BACKGROUND: Unraveling the signaling pathways responsible for the establishment of a metastatic phenotype in carcinoma cells is critically important for understanding the pathology of cancer. The acquisition of cell motility is a key property of metastatic tumor cells and is a prerequisite for invas...

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Detalhes bibliográficos
Main Authors: Cai, Kun, Mulatz, Kirk, Ard, Ryan, Nguyen, Thanh, Gee, Stephen H
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995506/
https://ncbi.nlm.nih.gov/pubmed/24646293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-208
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