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Diacylglycerol kinase ζ regulates RhoA activation via a kinase-independent scaffolding mechanism

Rho GTPases share a common inhibitor, Rho guanine nucleotide dissociation inhibitor (RhoGDI), which regulates their expression levels, membrane localization, and activation state. The selective dissociation of individual Rho GTPases from RhoGDI ensures appropriate responses to cellular signals, but...

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Detalhes bibliográficos
Main Authors: Ard, Ryan, Mulatz, Kirk, Abramovici, Hanan, Maillet, Jean-Christian, Fottinger, Alexandra, Foley, Tanya, Byham, Michèle-Renée, Iqbal, Tasfia Ahmed, Yoneda, Atsuko, Couchman, John R., Parks, Robin J., Gee, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3469516/
https://ncbi.nlm.nih.gov/pubmed/22918940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-01-0026
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