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Conventional NK cells can produce IL-22 and promote host defense in K. pneumoniae pneumonia()

It has been reported that host defense against pulmonary K. pneumoniae infection requires IL-22, which has been proposed to be of T cell origin. Supporting a role for IL-22, we found that Il22(−/−) mice had decreased survival as compared with wild type mice after intratracheal infection with K. pneu...

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Detalhes bibliográficos
Main Authors: Xu, Xin, Weiss, Ido D., Zhang, Hongwei, Singh, Satya P., Wynn, Thomas A., Wilson, Mark S., Farber, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995347/
https://ncbi.nlm.nih.gov/pubmed/24442439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300039
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