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Genetic Exploration of the Exit from Self-Renewal Using Haploid Embryonic Stem Cells
Self-renewal circuitry in embryonic stem cells (ESCs) is increasingly defined. How the robust pluripotency program is dissolved to enable fate transition is less appreciated. Here we develop a forward genetic approach using haploid ESCs. We created libraries of transposon integrations and screened f...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cell Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3995090/ https://ncbi.nlm.nih.gov/pubmed/24412312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.12.008 |
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