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The ground state of embryonic stem cell self-renewal

In the three decades since pluripotent mouse embryonic stem (ES) cells were first described(1,2) they have been derived and maintained by using various empirical combinations of feeder cells, conditioned media, cytokines, growth factors, hormones, fetal calf serum, and serum extracts(1–7). Consequen...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Ying, Qi-Long, Wray, Jason, Nichols, Jennifer, Batlle-Morera, Laura, Doble, Bradley, Woodgett, James, Cohen, Philip, Smith, Austin
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328678/
https://ncbi.nlm.nih.gov/pubmed/18497825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06968
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