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Heparan Sulfate Is Required for Embryonic Stem Cells to Exit from Self-renewal
Pluripotent embryonic stem cells (ESCs) must select between alternative fates of self-renewal and lineage commitment at each division during continuous proliferation. Heparan sulfate (HS) is a highly sulfated polysaccharide and is present abundantly on the ESC surface. In this study, we investigated...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820816/ https://ncbi.nlm.nih.gov/pubmed/20022960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.066837 |
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