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Heparan Sulfate Is Required for Embryonic Stem Cells to Exit from Self-renewal

Pluripotent embryonic stem cells (ESCs) must select between alternative fates of self-renewal and lineage commitment at each division during continuous proliferation. Heparan sulfate (HS) is a highly sulfated polysaccharide and is present abundantly on the ESC surface. In this study, we investigated...

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Detalhes bibliográficos
Main Authors: Kraushaar, Daniel C., Yamaguchi, Yu, Wang, Lianchun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820816/
https://ncbi.nlm.nih.gov/pubmed/20022960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.066837
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