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Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition

Epidermal barrier acquisition during late murine gestation is accompanied by an increase in Akt kinase activity and cJun dephosphorlyation. The latter is directed by the Ppp2r2a regulatory subunit of the Pp2a phosphatase. This was accompanied by a change of Claudin-1 localisation to the cell surface...

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Detalhes bibliográficos
Main Authors: Youssef, G., Gerner, L., Naeem, A.S., Ralph, O., Ono, M., O’Neill, C.A., O’Shaughnessy, R.F.L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995087/
https://ncbi.nlm.nih.gov/pubmed/23685254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2013.04.034
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