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AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation
Nuclear degradation is a key stage in keratinocyte terminal differentiation and the formation of the cornified envelope that comprises the majority of epidermal barrier function. Parakeratosis, the retention of nuclear material in the cornified layer of the epidermis, is a common histological observ...
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Publicado no: | Cell Death Differ |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4816115/ https://ncbi.nlm.nih.gov/pubmed/26045045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.62 |
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