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Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1–deficient mice

The tight junction (TJ) and its adhesion molecules, claudins, are responsible for the barrier function of simple epithelia, but TJs have not been thought to play an important role in the barrier function of mammalian stratified epithelia, including the epidermis. Here we generated claudin-1–deficien...

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Detalhes bibliográficos
Main Authors: Furuse, Mikio, Hata, Masaki, Furuse, Kyoko, Yoshida, Yoko, Haratake, Akinori, Sugitani, Yoshinobu, Noda, Tetsuo, Kubo, Akiharu, Tsukita, Shoichiro
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173463/
https://ncbi.nlm.nih.gov/pubmed/11889141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200110122
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