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Claudin-based tight junctions are crucial for the mammalian epidermal barrier: a lesson from claudin-1–deficient mice

The tight junction (TJ) and its adhesion molecules, claudins, are responsible for the barrier function of simple epithelia, but TJs have not been thought to play an important role in the barrier function of mammalian stratified epithelia, including the epidermis. Here we generated claudin-1–deficien...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Furuse, Mikio, Hata, Masaki, Furuse, Kyoko, Yoshida, Yoko, Haratake, Akinori, Sugitani, Yoshinobu, Noda, Tetsuo, Kubo, Akiharu, Tsukita, Shoichiro
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2002
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173463/
https://ncbi.nlm.nih.gov/pubmed/11889141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200110122
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