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Inhibition of Rab5 Activation During Insulin Receptor-Mediated Endocytosis

Activation of receptor tyrosine kinases is a key feature in receptor signaling and membrane trafficking processes. In this study, we found that the insulin receptor tyrosine kinase activity is required for fusion between early endosomes. AG1024, a receptor tyrosine kinase inhibitor, blocked the in v...

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Detalhes bibliográficos
Main Authors: Jozic, Ivan, Blanco, Gustavo, Barbieri, M. Alejandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995085/
https://ncbi.nlm.nih.gov/pubmed/24765621
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