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Distinct phenotypes of new transmembrane-domain neuregulin 1 mutant mice and the rescue effects of valproate on the observed schizophrenia-related cognitive deficits

Accumulating evidence suggests that neuregulin 1 (NRG1) might be involved in the neurodevelopment, neural plasticity, GABAergic neurotransmission, and pathogenesis of schizophrenia. NRG1 is abundantly expressed in the hippocampus, and emerging studies have begun to reveal the link between NRG1 signa...

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Detalhes bibliográficos
Main Authors: Pei, Ju-Chun, Liu, Chih-Min, Lai, Wen-Sung
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995064/
https://ncbi.nlm.nih.gov/pubmed/24782733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2014.00126
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