Neuregulin 1 Expression and Electrophysiological Abnormalities in the Neuregulin 1 Transmembrane Domain Heterozygous Mutant Mouse

BACKGROUND: The Neuregulin 1 transmembrane domain heterozygous mutant (Nrg1 TM HET) mouse is used to investigate the role of Nrg1 in brain function and schizophrenia-like behavioural phenotypes. However, the molecular alterations in brain Nrg1 expression that underpin the behavioural observations ha...

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Pubblicato in:PLoS One
Autori principali: Long, Leonora E., Anderson, Paul, Frank, Elisabeth, Shaw, Alex, Liu, Shijie, Huang, Xu-Feng, Pinault, Didier, Karl, Tim, O’Brien, Terence J., Shannon Weickert, Cynthia, Jones, Nigel C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437646/
https://ncbi.nlm.nih.gov/pubmed/25992564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124114
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