In vivo detection of peripherin-specific autoreactive B cells during type 1 diabetes pathogenesis()

Autoreactive B cells are essential for the pathogenesis of type 1 diabetes. The genesis and dynamics of autoreactive B cells remain unknown. Here, we analyzed the immune response in the NOD mouse model to the neuronal protein peripherin (PRPH), a target antigen of islet-infiltrating B cells. PRPH au...

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Autors principals: Garabatos, Nahir, Alvarez, Raimon, Carrillo, Jorge, Carrascal, Jorge, Izquierdo, Cristina, Chapman, Harold D., Presa, Maximiliano, Mora, Conchi, Serreze, David V., Verdaguer, Joan, Stratmann, Thomas
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994320/
https://ncbi.nlm.nih.gov/pubmed/24610011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301053
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