Lack of Salt-Inducible Kinase 2 (SIK2) Prevents the Development of Cardiac Hypertrophy in Response to Chronic High-Salt Intake

Cardiac left ventricle hypertrophy (LVH) constitutes a major risk factor for heart failure. Although LVH is most commonly caused by chronic elevation in arterial blood pressure, reduction of blood pressure to normal levels does not always result in regression of LVH, suggesting that additional facto...

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Autores principales: Popov, Sergej, Takemori, Hiroshi, Tokudome, Takeshi, Mao, Yuanjie, Otani, Kentaro, Mochizuki, Naoki, Pires, Nuno, Pinho, Maria João, Franco-Cereceda, Anders, Torielli, Lucia, Ferrandi, Mara, Hamsten, Anders, Soares-da-Silva, Patricio, Eriksson, Per, Bertorello, Alejandro M., Brion, Laura
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994160/
https://ncbi.nlm.nih.gov/pubmed/24752134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095771
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