Lack of Salt-Inducible Kinase 2 (SIK2) Prevents the Development of Cardiac Hypertrophy in Response to Chronic High-Salt Intake

Cardiac left ventricle hypertrophy (LVH) constitutes a major risk factor for heart failure. Although LVH is most commonly caused by chronic elevation in arterial blood pressure, reduction of blood pressure to normal levels does not always result in regression of LVH, suggesting that additional facto...

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Main Authors: Popov, Sergej, Takemori, Hiroshi, Tokudome, Takeshi, Mao, Yuanjie, Otani, Kentaro, Mochizuki, Naoki, Pires, Nuno, Pinho, Maria João, Franco-Cereceda, Anders, Torielli, Lucia, Ferrandi, Mara, Hamsten, Anders, Soares-da-Silva, Patricio, Eriksson, Per, Bertorello, Alejandro M., Brion, Laura
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994160/
https://ncbi.nlm.nih.gov/pubmed/24752134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095771
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