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Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition.

Three of the predominant features of apoptosis are internucleosomal DNA fragmentation, plasma membrane bleb formation, and retraction of cell processes. We demonstrate that actin is a substrate for the proapoptotic cysteine protease interleukin 1beta-converting enzyme. Actin cleaved by interleukin 1...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Kayalar, C, Ord, T, Testa, M P, Zhong, L T, Bredesen, D E
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1996
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39941/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700913/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.2234
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