Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition.

Three of the predominant features of apoptosis are internucleosomal DNA fragmentation, plasma membrane bleb formation, and retraction of cell processes. We demonstrate that actin is a substrate for the proapoptotic cysteine protease interleukin 1beta-converting enzyme. Actin cleaved by interleukin 1...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Kayalar, C, Ord, T, Testa, M P, Zhong, L T, Bredesen, D E
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1996
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39941/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8700913/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.5.2234
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