TAT-Protein Blockade during Ischemia/Reperfusion Reveals Critical Role for p85 PI3K-PTEN Interaction in Cardiomyocyte Injury

Recent work shows that cooling protection after mouse cardiac arrest and cardiomyocyte ischemia is mediated by Akt activation. The PI3K p85 subunit can either augment or inhibit Akt activation depending on its binding to p110 or PTEN respectively. To further clarify the role of PI3K p85 in cardiopro...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zhu, Xiangdong, Shao, Zuo-Hui, Li, Changqing, Li, Jing, Zhong, Qiang, Learoyd, Jonathan, Meliton, Angelo, Meliton, Lucille, Leff, Alan R., Vanden Hoek, Terry L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994094/
https://ncbi.nlm.nih.gov/pubmed/24752319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095622
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge