High-Affinity Recombinant Antibody Fragments (Fabs) Can Be Applied in Peptide Enrichment Immuno-MRM Assays

[Image: see text] High-affinity antibodies binding to linear peptides in solution are a prerequisite for performing immuno-MRM, an emerging technology for protein quantitation with high precision and specificity using peptide immunoaffinity enrichment coupled to stable isotope dilution and targeted...

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Autori principali: Whiteaker, Jeffrey R., Zhao, Lei, Frisch, Christian, Ylera, Francisco, Harth, Stefan, Knappik, Achim, Paulovich, Amanda G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993957/
https://ncbi.nlm.nih.gov/pubmed/24568200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr4009404
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