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Influence of Oligospermines Architecture on Their Suitability for siRNA Delivery
[Image: see text] Spermines are naturally abundant polyamines that partially condense nucleic acids and exhibit the proton-sponge effect in an acidic environment. However, spermines show a limited efficiency for transfecting nucleic acids because of their low molecular weight. Therefore, spermines n...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3993926/ https://ncbi.nlm.nih.gov/pubmed/24552396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm401849d |
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