Repression of the Proapoptotic Cellular BIK/NBK Gene by Epstein-Barr Virus Antagonizes Transforming Growth Factor β1-Induced B-Cell Apoptosis

The Epstein-Barr virus (EBV) establishes a lifelong latent infection in humans. EBV infection of primary B cells causes cell activation and proliferation, a process driven by the viral latency III gene expression program, which includes EBV nuclear proteins (EBNAs), latent membrane proteins, and unt...

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Main Authors: Campion, Eva M., Hakimjavadi, Roya, Loughran, Sinéad T., Phelan, Susan, Smith, Sinéad M., D'Souza, Brendan N., Tierney, Rosemary J., Bell, Andrew I., Cahill, Paul A., Walls, Dermot
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993823/
https://ncbi.nlm.nih.gov/pubmed/24554662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03642-13
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