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Adenovirus-Based Vaccines against Rhesus Lymphocryptovirus EBNA-1 Induce Expansion of Specific CD8(+) and CD4(+) T Cells in Persistently Infected Rhesus Macaques

The impact of Epstein-Barr virus (EBV) on human health is substantial, but vaccines that prevent primary EBV infections or treat EBV-associated diseases are not yet available. The Epstein-Barr nuclear antigen 1 (EBNA-1) is an important target for vaccination because it is the only protein expressed...

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Bibliografske podrobnosti
Main Authors: Leskowitz, R., Fogg, M. H., Zhou, X. Y., Kaur, A., Silveira, E. L. V., Villinger, F., Lieberman, P. M., Wang, F., Ertl, H. C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993789/
https://ncbi.nlm.nih.gov/pubmed/24522914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03744-13
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