Therapeutic Vaccination against the Rhesus Lymphocryptovirus EBNA-1 Homologue, rhEBNA-1, Elicits T Cell Responses to Novel Epitopes in Rhesus Macaques

Epstein-Barr virus (EBV) is a vaccine/immunotherapy target due to its association with several human malignancies. EBNA-1 is an EBV protein consistently expressed in all EBV-associated cancers. Herein, EBNA-1-specific T cell epitopes were evaluated after AdC–rhEBNA-1 immunizations in chronically lym...

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Detalhes bibliográficos
Main Authors: Silveira, Eduardo L. V., Fogg, Mark H., Leskowitz, Rachel M., Ertl, Hildegund C., Wiseman, Roger W., O'Connor, David H., Lieberman, Paul, Wang, Fred, Villinger, Francois
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3838282/
https://ncbi.nlm.nih.gov/pubmed/24089556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01947-13
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