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Aminodiols via Stereocontrolled Oxidation of Methyleneaziridines

[Image: see text] A highly diastereoselective Ru-catalyzed oxidation/reduction sequence of bicyclic methyleneaziridines provides a facile route to complex 1-amino-2,3-diol motifs. The relative anti stereochemistry between the amine and the vicinal alcohol are proposed to result from 1,3-bischelation...

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Autori principali: Rigoli, Jared W., Guzei, Ilia A., Schomaker, Jennifer M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2014
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993784/
https://ncbi.nlm.nih.gov/pubmed/24617556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol5003576
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