TRIM5α and TRIM22 Are Differentially Regulated According to HIV-1 Infection Phase and Compartment

The antiviral role of TRIM E3 ligases in vivo is not fully understood. To test the hypothesis that TRIM5α and TRIM22 have differential transcriptional regulation and distinct anti-HIV roles according to infection phase and compartment, we measured TRIM5α, TRIM22, and type I interferon (IFN-I)-induci...

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Autori principali: Singh, Ravesh, Patel, Vinod, Mureithi, Marianne W., Naranbhai, Vivek, Ramsuran, Duran, Tulsi, Sahil, Hiramen, Keshni, Werner, Lise, Mlisana, Koleka, Altfeld, Marcus, Luban, Jeremy, Kasprowicz, Victoria, Dheda, Keertan, Abdool Karim, Salim S., Ndung'u, Thumbi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Pathogenesis and Immunity
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993776/
https://ncbi.nlm.nih.gov/pubmed/24478420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03603-13
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