TRIM5α and TRIM22 Are Differentially Regulated According to HIV-1 Infection Phase and Compartment

The antiviral role of TRIM E3 ligases in vivo is not fully understood. To test the hypothesis that TRIM5α and TRIM22 have differential transcriptional regulation and distinct anti-HIV roles according to infection phase and compartment, we measured TRIM5α, TRIM22, and type I interferon (IFN-I)-induci...

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Detalhes bibliográficos
Main Authors: Singh, Ravesh, Patel, Vinod, Mureithi, Marianne W., Naranbhai, Vivek, Ramsuran, Duran, Tulsi, Sahil, Hiramen, Keshni, Werner, Lise, Mlisana, Koleka, Altfeld, Marcus, Luban, Jeremy, Kasprowicz, Victoria, Dheda, Keertan, Abdool Karim, Salim S., Ndung'u, Thumbi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993776/
https://ncbi.nlm.nih.gov/pubmed/24478420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03603-13
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