Thyroid Hormone Signaling In Vivo Requires a Balance between Coactivators and Corepressors

Resistance to thyroid hormone (RTH), a human syndrome, is characterized by high thyroid hormone (TH) and thyroid-stimulating hormone (TSH) levels. Mice with mutations in the thyroid hormone receptor beta (TRβ) gene that cannot bind steroid receptor coactivator 1 (SRC-1) and Src-1(−/−) mice both have...

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Bibliographic Details
Main Authors: Vella, Kristen R., Ramadoss, Preeti, Costa-e-Sousa, Ricardo H., Astapova, Inna, Ye, Felix D., Holtz, Kaila A., Harris, Jamie C., Hollenberg, Anthony N.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993596/
https://ncbi.nlm.nih.gov/pubmed/24550004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00129-14
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