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LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the cSMAC and exclusion of CD45 from the immunological synapse()

T cell activation is associated with a dramatic reorganization of cell surface proteins and associated signaling components into discrete subdomains within the immunological synapse in T cell:antigen presenting cell conjugates. However, the signals that direct the localization of these proteins and...

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Detalles Bibliográficos
Main Authors: Graf, Beth, Bushnell, Timothy, Miller, Jim
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993012/
https://ncbi.nlm.nih.gov/pubmed/17641028
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