Cargando...
Signals and sequences that control CD28 localization to the central region of the immunological synapse
During T cell interaction with APC, CD28 is recruited to the central region (cSMAC) of the immunological synapse. CD28-mediated signaling through PI3K results in the recruitment of PKCθ to the cSMAC, activation of NF-κB, and upregulation of IL-2 transcription. However, the mechanism that mediates CD...
Gardado en:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3993010/ https://ncbi.nlm.nih.gov/pubmed/19017952 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|