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Signals and sequences that control CD28 localization to the central region of the immunological synapse
During T cell interaction with APC, CD28 is recruited to the central region (cSMAC) of the immunological synapse. CD28-mediated signaling through PI3K results in the recruitment of PKCθ to the cSMAC, activation of NF-κB, and upregulation of IL-2 transcription. However, the mechanism that mediates CD...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3993010/ https://ncbi.nlm.nih.gov/pubmed/19017952 |
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