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A role for inside-out signaling in T cell receptor regulation of CD28 ligand binding
Efficient T cell activation depends on the engagement of both TCR and CD28, although the molecular mechanisms that control this signal integration are not fully understood. Using fluorescence resonance energy transfer, we show that T cell activation can drive a reorientation of the cytosolic tails o...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3244936/ https://ncbi.nlm.nih.gov/pubmed/22068237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102497 |
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