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Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses
Interactions between the herpesvirus entry mediator (HVEM) and the B- and T-lymphocyte attenuator (BTLA) inhibit B and T cell activation. HVEM-BTLA interactions are blocked by herpes simplex virus (HSV) glycoprotein D (gD) through binding of its N-terminal domain to the BTLA binding site of HVEM. In...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3992986/ https://ncbi.nlm.nih.gov/pubmed/18193057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1704 |
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