Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses

Interactions between the herpesvirus entry mediator (HVEM) and the B- and T-lymphocyte attenuator (BTLA) inhibit B and T cell activation. HVEM-BTLA interactions are blocked by herpes simplex virus (HSV) glycoprotein D (gD) through binding of its N-terminal domain to the BTLA binding site of HVEM. In...

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Detalhes bibliográficos
Main Authors: Lasaro, Marcio O, Tatsis, Nia, Hensley, Scott E, Whitbeck, J Charles, Lin, Shih-Wen, Rux, John J, Wherry, E John, Cohen, Gary H, Eisenberg, Roselyn J, Ertl, Hildegund C
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992986/
https://ncbi.nlm.nih.gov/pubmed/18193057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1704
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