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Accurate Zygote-Specific SNP Discrimination Using Microfluidic Electrochemical DNA Melt Curves()

We report the first electrochemical SNP detection system that can accurately discriminate homozygous and heterozygous genotypes using microfluidics technology. To achieve this, our system performs real-time melt-curve analysis of surface immobilized hybridization probe. As an example, we used our se...

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Detalhes bibliográficos
Main Authors: Yang, Allen H. J., Hsieh, Kuangwen, Patterson, Adriana S., Ferguson, B. Scott, Eisenstein, Michael, Plaxco, Kevin W., Soh, H. Tom
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992926/
https://ncbi.nlm.nih.gov/pubmed/24520069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201310059
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