Accurate Zygote-Specific SNP Discrimination Using Microfluidic Electrochemical DNA Melt Curves()

We report the first electrochemical SNP detection system that can accurately discriminate homozygous and heterozygous genotypes using microfluidics technology. To achieve this, our system performs real-time melt-curve analysis of surface immobilized hybridization probe. As an example, we used our se...

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Detaylı Bibliyografya
Asıl Yazarlar: Yang, Allen H. J., Hsieh, Kuangwen, Patterson, Adriana S., Ferguson, B. Scott, Eisenstein, Michael, Plaxco, Kevin W., Soh, H. Tom
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992926/
https://ncbi.nlm.nih.gov/pubmed/24520069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201310059
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