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Electrochemical DNA Detection via Exonuclease and Target-Catalyzed Transformation of Surface-Bound Probes
We report a single-step, single reagent, label-free, isothermal electrochemical DNA sensor based on the phenomenon of target-recycling. The sensor exploits strand-specific exonuclease activity to achieve selective enzymatic digestion of target/probe duplexes. This results in a permanent change in th...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883016/ https://ncbi.nlm.nih.gov/pubmed/20232926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/la100227s |
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