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Identifying regulatory mechanisms underlying tumorigenesis using locus expression signature analysis

Retroviral insertional mutagenesis is a powerful tool for identifying putative cancer genes in mice. To uncover the regulatory mechanisms by which common insertion loci affect downstream processes, we supplemented genotyping data with genome-wide mRNA expression profiling data for 97 tumors induced...

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Détails bibliographiques
Auteurs principaux: Lee, Eunjee, de Ridder, Jeroen, Kool, Jaap, Wessels, Lodewyk F. A., Bussemaker, Harmen J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992641/
https://ncbi.nlm.nih.gov/pubmed/24706889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309293111
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