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Arachidonic acid induction of Rho-mediated transendothelial migration in prostate cancer

BACKGROUND: Bone metastases in prostate cancer (CaP) result in CaP-related morbidity/mortality. The omega-6 polyunsaturated fatty acid (PUFA) arachidonic acid (AA) and lipophilic statins affect metastasis-like behaviour in CaP cells, regulating the critical metastatic step of CaP migration to the bo...

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Main Authors: Brown, M, Roulson, J-A, Hart, C A, Tawadros, T, Clarke, N W
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992515/
https://ncbi.nlm.nih.gov/pubmed/24595005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.99
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