Ligand-independent activation of EphA2 by arachidonic acid induces metastasis-like behaviour in prostate cancer cells

BACKGROUND: High intake of omega-6 polyunsaturated fatty acids (PUFA) has been associated with clinical progression in prostate cancer (CaP). This study investigates the signalling mechanism by which the omega-6 PUFA arachidonic acid (AA) induces prostatic cellular migration to bone marrow stroma. M...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tawadros, T, Brown, M D, Hart, C A, Clarke, N W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2012
Pynciau:
Molecular Diagnostics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493871/
https://ncbi.nlm.nih.gov/pubmed/23037715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.457
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