Amphotericin forms an extramembranous and fungicidal sterol sponge

Amphotericin has remained the powerful but highly toxic last line of defense in treating life-threatening fungal infections in humans for over 50 years with minimal development of microbial resistance. Understanding how this small molecule kills yeast is thus critical for guiding development of deri...

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Detaylı Bibliyografya
Asıl Yazarlar: Anderson, Thomas M., Clay, Mary C., Cioffi, Alexander G., Diaz, Katrina A., Hisao, Grant S., Tuttle, Marcus D., Nieuwkoop, Andrew J., Comellas, Gemma, Maryum, Nashrah, Wang, Shu, Uno, Brice E., Wildeman, Erin L., Gonen, Tamir, Rienstra, Chad M., Burke, Martin D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992202/
https://ncbi.nlm.nih.gov/pubmed/24681535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1496
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