Nanoparticles with Surface Antibody Against CD98 and Carrying CD98 Small Interfering RNA Reduce Colitis in Mice

BACKGROUND & AIMS: Nanoparticles have been explored as carriers of small interfering RNAs (siRNAs), and might developed to treat inflammatory bowel disease (IBD). Overexpression of CD98 on the surface of colonic epithelial cells and macrophages promotes development and progression of IBD. We dev...

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Detaylı Bibliyografya
Asıl Yazarlar: Xiao, Bo, Laroui, Hamed, Viennois, Emilie, Ayyadurai, Saravanan, Charania, Moiz A., Zhang, Yuchen, Zhang, Zhan, Baker, Mark T., Zhang, Benyue, Gewirtz, Andrew T., Merlin, Didier
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992175/
https://ncbi.nlm.nih.gov/pubmed/24503126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.01.056
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